Retatrutide price in 2026

Retatrutide price at a glance

The retatrutide price you pay depends almost entirely on two things: which vendor you buy from and which vial size you choose. Across the six US-facing research vendors compared here, the cost works out to between $5.00 and $10.50 per mg, which means the same 10 mg of peptide costs $67.99 at Astral and $105 at the most expensive vendor. The cheapest way to buy is almost always a larger vial from a vendor that prices every size competitively.

Astral is that vendor at 10 mg and 20 mg. Its GLP-3 RT (Astral's name for retatrutide) is $67.99 for 10 mg, $117.99 for 20 mg and $157.99 for 30 mg, or $6.80, $5.90 and $5.27 per mg, with volume pricing on top at two, three and ten or more vials.

See GLP-3 RT pricing at Astral →

Retatrutide price by vial size and vendor (as of November 12, 2026)

Prices as listed on each vendor's site on November 12, 2026. Price per mg is the vial price divided by the labeled milligrams.

HEEZ Research and American Peptides also list 20 mg vials, and American Peptides lists 48 and 60 mg vials, but show no clear single-vial price for those sizes, so they are not in the table. Kylo Peptides sells through a $497 lifetime membership advertised as 50% off, with no clear single-vial price, so it cannot be placed in a per-mg table at all.

The table says three things. Astral has the lowest price per mg at 10 mg and at 20 mg. At 30 mg, Prism Labs is cheaper per mg than Astral, $5.00 against $5.27. And True Peptides' 40 mg vial, at $5.13 per mg, is the second-cheapest line in the table but comes from a vendor whose 10 mg and 20 mg prices are among the highest.

What drives the price of retatrutide?

Retatrutide is a large synthetic peptide, with a molecular weight around 4,700, built from a long chain of amino acids with modifications. Making it means many sequential coupling steps, each of which loses a little yield, followed by purification and freeze-drying. Longer, modified peptides cost more per mg to make than short simple ones, and that cost floor is similar for every vendor that puts the labeled amount in the vial.

On top of synthesis cost, four things move the price you see:

• Vial size. The vial, cap, label, handling and shipping cost about the same whether 10 mg or 30 mg is inside, so bigger vials are cheaper per mg.
• Where it is made. A vendor that synthesizes and manufactures domestically carries US labor and facility costs. Astral manufactures in the United States and still prices below most of the field.
• Inventory. A vendor that holds its own stock, as Astral does in New York, bears carrying cost but controls what it ships. A drop-shipper has lower overhead and less control.
• Volume. Multi-vial pricing rewards larger orders. Astral discounts at two, three and ten or more vials; HEEZ sells three 10 mg vials for $200 and five for $300.

Why a retatrutide price far below the market is a warning

Because the synthesis cost floor is real, a vendor offering retatrutide at a fraction of the $5.00 to $10.50 per mg band is either taking a loss, under-filling the vial, selling something other than retatrutide, or planning not to ship at all. None of those is a bargain. Low purity and short-weight vials are the cheapest ways to hit a headline price, and the buyer cannot see either from the listing.

A sensible rule: treat any price more than a third below the cheapest reputable vendor at the same size as a question to answer before ordering, not a reason to order. Our guide to choosing a retatrutide vendor lists the other signals to check alongside price.

Retatrutide volume pricing: buying more than one vial

If your work needs several vials, the per-vial price is not the number to compare; the per-mg price at your order quantity is. Astral applies volume pricing to GLP-3 RT at two or more, three or more and ten or more vials, on every size, so a lab ordering ten 30 mg vials pays less per mg than the single-vial figure in the table. HEEZ Research's bundles work the same way for its 10 mg vial. American Peptides and Kylo Peptides list 48 or 60 mg vials, which may suit a bulk buyer if the per-mg figure holds up.

Before committing to a large order, confirm that you will use the material inside the vendor's stated window once reconstituted. A cheap vial you throw half of away is not cheap. Our home page covers which vial size to buy and how the six vendors compare beyond price.

How much will retatrutide cost when FDA approved?

As of November 12, 2026, there is no answer, and anyone giving you a dollar figure is guessing. Retatrutide is investigational and not approved. Eli Lilly has said it plans to submit a Biologics License Application to the FDA in the first quarter of 2027, covering obesity, knee osteoarthritis pain and obstructive sleep apnea, according to its July 2026 release. FDA review follows submission, and Lilly has not announced an approval date or a price.

That means an approved retatrutide product, if one comes, would not carry a price before late 2027 at the earliest, and the price would be set by Lilly at that time. The retatrutide price discussed on this page, by contrast, is for research-grade material sold to laboratories, which is a different product in a different market and will not be affected by Lilly's eventual list price.

Is a prescription required for retatrutide?

No prescription can exist for it today, because there is no approved product for a prescription to name. The clinical routes are Lilly's trials and its physician-initiated expanded access program, both listed on ClinicalTrials.gov. Research suppliers sell retatrutide to laboratories under research-use-only terms, not on prescription. Our page on whether retatrutide is legal to buy has the detail.

Retatrutide 30 mg vs 20 mg vs 10 mg: which size is cheapest?

Per mg, the 30 mg vial is cheapest at every vendor that sells one, and the 10 mg vial is most expensive. At Astral the drop is from $6.80 at 10 mg to $5.90 at 20 mg and $5.27 at 30 mg. At True Peptides it runs from $8.90 to $7.45 to $6.20, and at Prism from $6.25 to $5.00.

The cheapest size is therefore the largest one you will fully use within the vendor's reconstituted-use window. For a short run, a 10 mg vial at a higher per-mg price wastes less. For an ongoing program, buy 30 mg vials and take the volume discount. For the arithmetic on how much water a given vial takes, use Astral's peptide calculator.

Where to buy retatrutide at the best price

For 10 mg and 20 mg vials, Astral is the best retatrutide price in our comparison, and it is the only vendor that pairs that price with US synthesis and manufacture, its own New York inventory, three sizes and clean research-use framing. For a single 30 mg vial where only the per-mg figure matters, Prism Labs is a few cents per mg cheaper. Taken as a whole, Astral is in a class of its own, and the vendor we would order from.

Buy GLP-3 RT at Astral →